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Publications
We have significantly contributed to the understanding of health conditions through real-world data analysis. The insights gained from these studies have had a positive impact on clinical practice, leading to more personalised and effective care for patients.
Association of frequent short-acting beta-agonist inhaler prescriptions with acute cardiovascular events
25 Jul 2025
Pragmatic and Observational Research
Authors:
Paul E. Pfeffer, Heath Heatley, Richard Hubbard, John Townend, and David Price
Keywords:
asthma, COPD, short-acting β-agonist, overuse, acute cardiovascular events
Prevention of Cardiovascular and Other Systemic Adverse Outcomes in Patients with Asthma Treated with Biologics (SOLAR II)
19 May 2025
American Journal of Respiratory and Critical Care Medicine
Authors:
Mohsen Sadatsafavi, Trung N. Tran, Ghislaine Scelo, Ming-Ju Tsai, John Busby, Benjamin Emmanuel, Liam G. Heaney, Christine Jenkins, Flavia Hoyte, Giorgio Walter Canonica, Rohit Katial, Enrico Heffler, Eileen Wang, Francesca Puggioni, Michael E. Wechsler, Ledit R. F. Ardusso, Jorge Máspero, Martin Sivori, Cathy Emmas, Andrew N. Menzies-Gow, Neda Stjepanovic, Sinthia Z. Bosnic-Anticevich, Belinda Cochrane, Eve Denton, Peter G. Gibson, Mark Hew, Peter G. Middleton, Matthew J. Peters, Guy G. Brusselle, Renaud Louis, Florence Schleich, George C. Christoff, Todor A. Popov, Celine Bergeron, Mohit Bhutani, Kenneth R. Chapman, Andréanne Côté, Simon Couillard, Delbert R. Dorscheid, Libardo Jiménez-Maldonado, Ivan Solarte, Carlos A. Torres-Duque, Susanne Hansen, Celeste M. Porsbjerg, Charlotte Suppli Ulrik, Alan Altraja, Arnaud Bourdin, Konstantinos P. Exarchos, Athena Gogali, Konstantinos Kostikas, Michael P. Makris, Andriana I. Papaioannou, Patrick D. Mitchell, Takashi Iwanaga, Tatsuya Nagano, Yuji Tohda, Mona S. Al-Ahmad, Désirée Larenas-Linnemann, Bernt Bøgvald Aarli, Piotr Kuna, Cláudia Chaves Loureiro, Riyad Al-Lehebi, Adeeb A. Bulkhi, Wenjia Chen, Yah Ru Juang, Mariko Siyue Koh, Anqi Liu, Chin Kook Rhee, Borja G. Cosio, Luis Perez-de-Llano, Diahn-Warng Perng, Chau-Chyun Sheu, Hao-Chien Wang, Bassam Mahboub, Laila Salameh, David J. Jackson, Pujan H. Patel, Paul E. Pfeffer, Njira Lugogo, Roy Alton Pleasants, Aaron Beastall, Lakmini Bulathsinhala, Victoria Carter, Nevaashni Eleangovan, Kirsty Fletton, John Townend, Ruth B. Murray, David B. Price
Keywords:
Diabetes Mellitus, Adverse Cardiac Event, Cohort Studies
Impact of biologic initiation on oral corticosteroid use in the International Severe Asthma Registry and the Optimum Patient Care Research Database: a pooled analysis of real-world evidence (SOLAR I)
26 Apr 2025
The Journal of Allergy and Clinical Immunology: In Practice
Authors:
Wenjia Chen, Trung N. Tran, John Townend, George C. Christoff, Ming-Ju Tsai, Alan Altraja, Belinda Cochrane, Borja G. Cosio, Martin Sivori, Ruth B. Murray, Michael P. Makris, Ghislaine Scelo, Lakmini Bulathsinhala, Ledit R. F. Ardusso, María Eugenia Franchi, Jorge Máspero, Fernando Saldarini, Ana María Stok, Ana Giselle Tomaszuk, Anahí Yañez, Benjamin Emmanuel, Cathy Emmas, Konstantinos Kostikas, Andrew N. Menzies-Gow, Neda Stjepanovic, Sinthia Z. Bosnic-Anticevich, Eve Denton, Peter G. Gibson, Mark Hew, Christine Jenkins, Peter G. Middleton, Matthew J. Peters, John W. Upham, Guy G. Brusselle, Renaud Louis, Florence Schleich, Paulo Márcio Pitrez, Todor A. Popov, Celine Bergeron, Mohit Bhutani, Kenneth R. Chapman, Andréanne Côté, Simon Couillard, Delbert R. Dorscheid, M. Diane Lougheed, Mohsen Sadatsafavi, Carlos Andrés Celis-Preciado, Libardo Jiménez-Maldonado, Bellanid Rodríguez-Cáceres, Diana Jimena Cano Rosales, Ivan Solarte, Carlos A. Torres-Duque, Susanne Hansen, Celeste M. Porsbjerg, Charlotte Suppli Ulrik, Arnaud Bourdin, Petros Bakakos, Konstantinos P. Exarchos, Athena Gogali, Aggelos A. Ladias, Nikolaos G. Papadopoulos, Andriana I. Papaioannou, Richard W. Costello, Breda Cushen, Patrick D. Mitchell, Giorgio Walter Canonica, Enrico Heffler, Francesca Puggioni, Takashi Iwanaga, Tatsuya Nagano, Yuji Tohda, Mona S. Al-Ahmad, Désirée Larenas-Linnemann, Bernt Bøgvald Aarli, Sverre Lehmann, Piotr Kuna, José Alberto Ferreira, João A. Fonseca, Cláudia Chaves Loureiro, Riyad Al-Lehebi, Adeeb A. Bulkhi, Yah Ru Juang, Mariko Siyue Koh, Anqi Liu, Chin Kook Rhee, Luis Perez-de-Llano, Pin-Kuei Fu, Diahn-Warng Perng, Chau-Chyun Sheu, Hao-Chien Wang, Bassam Mahboub, Laila Salameh, John Busby, Liam G. Heaney, David J. Jackson, Pujan H. Patel, Paul E. Pfeffer, Flavia Hoyte, Rohit Katial, Njira Lugogo, Roy Alton Pleasants, Eileen Wang, Michael E. Wechsler, Aaron Beastall, Victoria Carter, Nevaashni Eleangovan, Kirsty Fletton, David B. Price
Keywords:
Severe asthma, difficult-to-treat asthma, oral corticosteroids, steroids, biologics, monoclonal antibody, real-world evidence, anti-IL5, anti-IL4/13, anti-IgE
PRagmatic EVAluation of an Improvement program for people Living with modifiable high-risk COPD (PREVAIL) vs usual care: protocol for a cluster randomized trial
25 Apr 2025
Journal of the COPD Foundation
Authors:
Katherine Hickman, Yasir Tarabichi, Andrew P. Dickens, Rachel Pullen, Margee Kerr, Amy Couper, Alexander Evans, James Gatenby, Luis Alves, Cono Ariti, Mona Bafadhel, Victoria Carter, James Chalmers, Rongchang Chen, Graham Devereux, M. Bradley Drummond, J. Martin Gibson, David M. G. Halpin, MeiLan K. Han, Nicola A. Hanania, John R. Hurst, Alan Kaplan, Konstantinos Kostikas, Barry Make, Douglas Mapel, Jonathan Marshall, Fernando Martinez, Catherine Meldrum, Marije van Melle, Marc Miravitlles, Tamsin Morris, Hana Mullerova, Ruth Murray, Shigeo Muro, Clementine Nordon, Jill Ohar, Wilson Pace, Michael Pollack, Jennifer K. Quint, Anita Sharma, Dave Singh, Mukesh Singh, Frank Trudo, Dennis Williams, Tom Wilkinson, Tonya Winders, David Price.
Keywords:
COPD, quality improvement, CONQUEST, high-risk, MACRE
The real world impact of Glucagon-like peptide 1 receptor agonists on asthma control in people with obesity and high-risk asthma
8 Apr 2025
Advances in Therapy
Authors:
Alan Kaplan, Heath Heatley, John Townend, Derek Skinner, Victoria Carter, Richard Hubbard, Tan Tze Lee, Mariko Siyue Koh, David Price
Keywords:
Asthma, Obesity, Asthma outcomes, GLP1s
Predicting risk of morbidities associated with oral corticosteroid prescription for asthma
25 Mar 2025
Journal of Asthma and Allergy
Authors:
Brooklyn Stanley, Jatin Chapaneri, Mina Khezrian, Ekaterina Maslova, Soram Patel, Mark Gurnell, Giorgio Walter Canonica, Helen K. Reddel, Liam G. Heaney, Arnaud Bourdin, David L. Neil, Victoria Carter, David Price
Keywords:
Optimum Patient Care Research Database, OPCRD, asthma, oral corticosteroids, risk assessment, diabetes, osteoporosis, cardiovascular disease
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